Psychologic stress and cancer
The objective of this ECERI programm is to study the potential links between psychological stress or trauma and cancer, by studying the neuro-endocrine-immune mechanisms that are at stake. This project is launched by oncologists, in collaboration with the Brain Research Institute in Zurich.
Pr Belpomme met Pr Isabelle Mansuy from the Brain Research Institute in Zurich in February 2013 to discuss the conditions of a collaborative research project on "Psychological Stress and Cancer." The project, to be achieved, requires a funding of 50,000 €, with the allocation of a researcher.
The protocol for this project was recently dsicussed during a meeting in Paris. Dr Philippe Irigaray will be the ECERI-ARTAC representative. The study will be activated September 2013.
Read more about this research area :
Bohacek, J, Gapp, K, Saab, B.J. and Mansuy I.M. (2013). Transgenerational epigenetic effects on brain functions. Biol. Psych. 73: 313-20.
Bohacek, J, and Mansuy I.M. (2013). Epigenetic inheritance of disease and disease risk. Neuropsychopharm. Rev. 38:220-36.Franklin T., Russig, H., Weiss, I.C., Gräff, J., Linder, N., Michalon, A., Vizi, S. and Mansuy I.M. (2010). Non-genomic transmission of the impact of early stress across generations. Biol. Psych. 68:408-15.
Franklin, T., Saab, B. J. and Mansuy I.M. (2012). The neural mechanisms of stress resilience and vulnerability. Neuron 75, 747-761.
Weiss, I.C., Franklin T., Vizi, S. and Mansuy I.M. (2011). Inheritable effect of unpredictable maternal separation on behavioral responses in mice. Frontiers in Behav. Neurosci. 5:1-12.
Franklin T., Linder, N., Russig, H., Thöny, B. and Mansuy I.M. (2011). Influence of early stress on social abilities and serotonergic function across generations in mice. PLoSONE. 6:21842.